Darren Fletcher, once again captain for the night, scored the winning spot-kick after Inter’s Marco Andreolli’s effort struck the bar.
Van Gaal fielded two almost completely different teams over the two halves, with the likes of Wayne Rooney, Nani, Juan Mata, and new signing Ander Herrera all given the chance to impress.
Check out the Manchester United lineup and full match highlights below:
Manchester United first half: Lindegaard; Smalling, Jones, Evans; Valencia, Fletcher, Herrera, Young, Mata; Rooney, Welbeck
Second half: De Gea; M Keane, Evans, Blackett; Young, Cleverley, Fletcher, Kagawa, Shaw; Zaha, Nani (Hernandez 77)