Arsene Wenger will be boosted with the return of midfielder Tomas Rosicky for this tie which might force him to change his plans a little bit.
In the defence, Wenger will deploy his best back four combinations. German defender Per Mertesacker will start alongside Laurent Koscielny while Bacary Sagna and Gibbs will play on the right and left back positions respectively.
The midfield duo is important here. Wenger in the press conference has pointed Marek Hamsik and Lorenzo Insigne as the main threat and there could be a temptation to play both Arteta and Flamini at the centre. But, with the form Aaron Ramsey is in, it is hard to see Wenger changing the system too much.
Serge Gnarby was impressive in the last match but Wenger probably won’t take the risk of throwing him against a strong Napoli side, especially when Rosicky is fit. In that situation, a trio of Rosicky, Ozil and Wilshere will form a balanced line-up.
Here is the probable formation for the Gunners:
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