The Reds currently lead City by six points and a victory this weekend would make them huge favourites to end their long wait for a league title.
Liverpool head into the game on the back of a narrow 2-1 win over Genk in the Champions League on Tuesday.
City were also in European action the following evening, recording a 1-1 draw at Atalanta.
Pep Guardiola’s side took four points off Liverpool last season, drawing at Anfield before securing a victory on home soil.
They also triumphed on penalties when the two sides met in the Community Shield earlier this season.
Confirmed starting line-ups:
— Liverpool FC (@LFC) November 10, 2019
How we’re lining-up at Anfield 💪
Bravo, Walker, Stones, Fernandinho (C), Angelino, Rodrigo, Gundogan, De Bruyne, Bernardo, Sterling, Aguero
Subs | Carson, Jesus, Silva, Mahrez, Cancelo, Otamendi, Foden
— Manchester City (@ManCity) November 10, 2019
City can ill-afford to be beaten by Liverpool and are strongly fancied to pick up three points this weekend. They are priced at odds of 7/4 with EagleBet to win the game and that looks good value.