The Gunners are heading into this tie on the back of a moral boosting 1-0 victory over their North London rivals, Tottenham. Arsene Wenger, the Arsenal manager, will be expecting a similar sort of result on Saturday as well.
Arsenal will still miss the services of key players like Mesut Ozil and Aaron Ramsey, while Alex Oxlade-Chamberlain should be fit enough to start, after suffering a minor calf problem that saw him getting withdrawn against Spurs in the second half.
The only decision Wenger will have to make is whether to include Flamini or not. Against a strong opposition like Chelsea, that too away from home, Wenger might be tempted to add enough defensive steel in the middle of the park.
This could be the possible line-up for the Gunners against Chelsea on Saturday.
Prediction: 1-1; Arsenal are still very much alive in the title-race and they are well capable of getting something out of this match.