Fulham would get a 2-1 advantage in the first leg at Craven Cottage on Thursday night.
They had most of the chances in the match and would lead 2-0 until a late second half goal from Wolfsburg. Neither team would score in the first 45 minutes but there would be three in the second half.
The goals for Fulham would come from Bobby Zamora in the 59th minute and Damien Duff in the 63rd minute. Fulham would have a few more chances in the match but Wolfsburg would be the next team to score. Alexander Madlung would get a crucial away goal with a header in the 89th minute.
The match would end at 2-1 and Wolfsburg will host the second leg.